Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models

Yong Ung Lee; Jian Luo; Eugene Sprague; Hai Chao Han

Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models

Yong Ung Lee, Jian Luo, Eugene Sprague, Hai Chao Han

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Arterial restenosis associated with intimai hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of reendothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.

Original language	English (US)
Title of host publication	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages	305-306
Number of pages	2
Edition	PART A
State	Published - 2009
Externally published	Yes
Event	10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States Duration: Jun 25 2008 → Jun 29 2008

Publication series

Name	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Number	PART A

Other

Other	10th ASME Summer Bioengineering Conference, SBC2008
Country/Territory	United States
City	Marco Island, FL
Period	6/25/08 → 6/29/08

ASJC Scopus subject areas

Biotechnology
Bioengineering
Biomedical Engineering

Cite this

Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models. / Lee, Yong Ung; Luo, Jian; Sprague, Eugene et al.
Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART A. ed. 2009. p. 305-306 (Proceedings of the ASME Summer Bioengineering Conference, SBC2008; No. PART A).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lee, YU, Luo, J, Sprague, E & Han, HC 2009, Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models. in Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART A edn, Proceedings of the ASME Summer Bioengineering Conference, SBC2008, no. PART A, pp. 305-306, 10th ASME Summer Bioengineering Conference, SBC2008, Marco Island, FL, United States, 6/25/08.

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abstract = "Arterial restenosis associated with intimai hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of reendothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.",

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Y1 - 2009

N2 - Arterial restenosis associated with intimai hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of reendothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.

AB - Arterial restenosis associated with intimai hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of reendothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.

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M3 - Conference contribution

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BT - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

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ER -

Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models

Abstract

Publication series

Other

ASJC Scopus subject areas

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