TY - JOUR
T1 - Fibrin-Associated Diffuse Large B Cell Lymphoma Found on Revision Arthroplasty of the Knee
AU - Hall, Jordan
AU - Kampfer, Craig
AU - Williams, Ned
AU - Osswald, Michael
AU - Bishop, Bradie
AU - Hall, Misty
AU - Alderete, Joseph
N1 - Publisher Copyright:
© Lippincott Williams & Wilkins.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - Fibrin-associated diffuse large B cell lymphoma (FA-DLBCL) is a rare Epstein-Barr viruspositive B cell lymphoma that is nonmass-forming, does not directly produce symptoms, and is incidentally discovered on histological examination of tissues excised for other reasons. Despite overlap in morphologic and immunophenotypic features with aggressive B cell neoplasms, FA-DLBCL shows an excellent clinical outcome, even with surgical excision alone. We report an extremely rare occurrence of FA-DLBCL found in association with a metallic implant on revision arthroplasty of the knee. This report also illustrates the need for an integrated multidisciplinary approach for accurate diagnosis and avoidance of overtreatment.
AB - Fibrin-associated diffuse large B cell lymphoma (FA-DLBCL) is a rare Epstein-Barr viruspositive B cell lymphoma that is nonmass-forming, does not directly produce symptoms, and is incidentally discovered on histological examination of tissues excised for other reasons. Despite overlap in morphologic and immunophenotypic features with aggressive B cell neoplasms, FA-DLBCL shows an excellent clinical outcome, even with surgical excision alone. We report an extremely rare occurrence of FA-DLBCL found in association with a metallic implant on revision arthroplasty of the knee. This report also illustrates the need for an integrated multidisciplinary approach for accurate diagnosis and avoidance of overtreatment.
KW - fibrin-associated (Epstein-Barr virus-positive) diffuse large B cell lymphoma (FA-DLBCL)
KW - foreign body
KW - multidisciplinary approach
KW - non-Hodgkin lymphoma
KW - orthopedic metallic implant
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U2 - 10.14423/SMJ.0000000000001321
DO - 10.14423/SMJ.0000000000001321
M3 - Article
C2 - 34729615
AN - SCOPUS:85121481373
SN - 0038-4348
VL - 114
SP - 708
EP - 713
JO - Southern medical journal
JF - Southern medical journal
IS - 11
ER -