Fenfluramine: Amphetamine congener that fails to maintain drug-taking behavior in the rhesus monkey

James H. Woods, Richard E. Tessel

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

Fenfluramine, over a dose range from 0.003 to 3 milligrams per kilogram of body weight, failed to maintain self-injection behavior in rhesus monkeys that had initiated and maintained responding for cocaine or methohexital. This absence of a positive reinforcing effect could not be attributed to a slow onset of drug effect or to the use of behaviorally inactive doses. Fenfluramine, because of its distinctive properties, may produce fewer problems of human abuse than do amphetamine-type agents.

Original languageEnglish (US)
Pages (from-to)1067-1069
Number of pages3
JournalScience
Volume185
Issue number4156
DOIs
StatePublished - 1974
Externally publishedYes

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