FASpecT/CT, A New SPECT/CT Acquisition with Higher Sensitivity and Efficiency in Radioiodine Thyroid Cancer Imaging

William T. Phillips, Vishal Kukkar, Gary L. Francis, Brandon C. Gorzell, Albert W. Cooper, Darlene F. Metter, Jack L. Lancaster

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Purpose This article demonstrates the use of a new SPECT/CT acquisition protocol in patients with differentiated thyroid cancer (DTC). Methods SPECT/CT scans (FASpecT/CT) with fewer angle acquisitions were retrospectively reviewed in 30 DTC patients treated with radioiodine at University Hospital, San Antonio, Tex, from July 2017 to March 2019. This FASpecT/CT of 12 versus 60 to 64 sampled views for convention SPECT was made possible by iterative reconstruction. Results The FASpecT/CT protocol was judged to increase lesion detection in patients with low count rates. Furthermore, in patients with higher count rates, this technique reduced the acquisition time. FASpecT/CT patient images are shown as case examples in 4 of the 30 patients reviewed. Conclusions This FASpecT/CT acquisition in radioiodine-treated DTC offers the potential of higher sensitivity for metastatic lymph node detection in low count rates and a significant decrease in imaging time in high count rates. These advantages make SPECT/CT imaging more acceptable for patients who have difficulty with longer imaging times, to include the pediatric population.

Original languageEnglish (US)
Pages (from-to)356-364
Number of pages9
JournalClinical nuclear medicine
Issue number5
StatePublished - May 1 2020


  • SPECT/CT imaging
  • fewer angle
  • iterative reconstruction
  • radioiodine
  • thyroid cancer

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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