Familial analysis of bipolar affective disorder using logistic models

John Blangero, Robert C. Elston

    Research output: Contribution to journalArticle

    11 Scopus citations

    Abstract

    Data on bipolar affective disorder in 187 pedigrees from the Collaborative Depression Study were analyzed using logistic models that have been extended to incorporate age of onset information. Logistic regression analysis and segregation analysis revealed evidence for complex familial effects on this disorder.

    Original languageEnglish (US)
    Pages (from-to)221-227
    Number of pages7
    JournalGenetic epidemiology
    Volume6
    Issue number1
    DOIs
    StatePublished - 1989

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    Keywords

    • age of onset
    • binary traits
    • logistic regression
    • segregation analysis

    ASJC Scopus subject areas

    • Epidemiology
    • Genetics(clinical)

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