False-positive interpretations in respiratory cytopathology: Exemplary cases and literature review

Maria Luisa C. Policarpio-Nicolas, Mark R. Wick

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Pulmonary cytology has progressed over the past decades because of advancement in imaging studies and increased confidence of pathologists in cytomorphologic diagnosis. It has an overall sensitivity and specificity ranging from ∼60 to 96%. However, even with the most conscientious laboratories, false-positive diagnoses of malignancy do occur in respiratory specimens, potentially resulting in unnecessary treatment and morbidity. Selected respiratory cytopathology cases with false-positive diagnoses are presented here, along with a review of pertinent literature and a discussion of possible steps to minimize the problem being considered.

Original languageEnglish (US)
Pages (from-to)13-19
Number of pages7
JournalDiagnostic cytopathology
Volume36
Issue number1
DOIs
StatePublished - Jan 2008

Keywords

  • False-positive results
  • Respiratory cytology

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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