Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration

Research output: Contribution to journalArticle

Abstract

Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

Original languageEnglish (US)
Pages (from-to)355-359
Number of pages5
JournalSubstance and Alcohol Actions/Misuse
Volume1
Issue number4
StatePublished - 1980

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Dronabinol
Luteinizing Hormone
Prolactin
Rats
Plasmas
Pineal Gland
Castration

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration",
abstract = "Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).",
author = "Johnson, {Linda Y} and Asch, {R. H.} and Reiter, {Russel J}",
year = "1980",
language = "English (US)",
volume = "1",
pages = "355--359",
journal = "Alcohol",
issn = "0741-8329",
publisher = "Elsevier Inc.",
number = "4",

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T1 - Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration

AU - Johnson, Linda Y

AU - Asch, R. H.

AU - Reiter, Russel J

PY - 1980

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N2 - Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

AB - Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

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