Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration

L. Y. Johnson, R. H. Asch, R. J. Reiter

Research output: Contribution to journalArticle

Abstract

Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

Original languageEnglish (US)
Pages (from-to)355-359
Number of pages5
JournalSubstance and Alcohol Actions/Misuse
Volume1
Issue number4
StatePublished - Dec 1 1980

ASJC Scopus subject areas

  • Medicine(all)

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