Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration

L. Y. Johnson; R. H. Asch; R. J. Reiter

Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ⁹-tetrahydrocannabinol administration

L. Y. Johnson, R. H. Asch, R. J. Reiter

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

Abstract

Δ⁹-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

Original language	English (US)
Pages (from-to)	355-359
Number of pages	5
Journal	Substance and Alcohol Actions/Misuse
Volume	1
Issue number	4
State	Published - Dec 1 1980

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration",

abstract = "Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).",

author = "Johnson, {L. Y.} and Asch, {R. H.} and Reiter, {R. J.}",

year = "1980",

month = dec,

day = "1",

language = "English (US)",

volume = "1",

pages = "355--359",

journal = "Alcohol",

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T1 - Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ9-tetrahydrocannabinol administration

AU - Johnson, L. Y.

AU - Asch, R. H.

AU - Reiter, R. J.

PY - 1980/12/1

Y1 - 1980/12/1

N2 - Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

AB - Δ9-Tetrahydrocannabinol (THC) (2.5 mg/kg BW) treatment acutely depressed plasma levels of luteinizing hormone and prolactin in cannulated rats ovariectomized five weeks earlier. Pinealectomy prior to castration did not eliminate or significantly modify these hormonal changes. Thus, these effects of THC do not appear to be mediated by the pineal gland or influenced by it under long photoperiodic conditions (14L:10D).

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ER -

Failure of pinealectomy to affect acute changes in plasma levels of luteinizing hormone and prolactin in ovariectomized rats following δ⁹-tetrahydrocannabinol administration

Abstract

ASJC Scopus subject areas

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