TY - JOUR
T1 - Fabrication and Characterization of PLA-PGA Orthopedic Implants
AU - Agrawal, C. Mauli
AU - Niederauer, Gabriele G.
AU - Athanasiou, Kyriacos A.
PY - 1995/9/1
Y1 - 1995/9/1
N2 - Fabrication methods and property characterization of polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are reviewed. Both of these aliphatic polyesters belong to the a-hydroxy group and biodegrade in a physiological environment to monomeric acids, which are readily processed and excreted from the body. The physical and mechanical characteristics discussed include molecular weight, crystallinity, stress–strain behavior, permeability, and melting/glass transition temperatures. The most common methods of fabricating PLA–PGA materials into medical devices are described.
AB - Fabrication methods and property characterization of polyglycolic acid (PGA), polylactic acid (PLA), and their copolymers are reviewed. Both of these aliphatic polyesters belong to the a-hydroxy group and biodegrade in a physiological environment to monomeric acids, which are readily processed and excreted from the body. The physical and mechanical characteristics discussed include molecular weight, crystallinity, stress–strain behavior, permeability, and melting/glass transition temperatures. The most common methods of fabricating PLA–PGA materials into medical devices are described.
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U2 - 10.1089/ten.1995.1.241
DO - 10.1089/ten.1995.1.241
M3 - Article
AN - SCOPUS:85016536822
SN - 1076-3279
VL - 1
SP - 241
EP - 252
JO - Tissue Engineering
JF - Tissue Engineering
IS - 3
ER -