Extracorporeal Therapies in the Treatment of Focal Segmental Glomerulosclerosis

Rupesh Raina, Joseph Wang, Aditya Sharma, Ronith Chakraborty

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations

Abstract

Focal segmental glomerulosclerosis (FSGS) is one of the most frequent and severe glomerular kidney disease with frequent progression to end-stage renal disease and a high rate of recurrence in renal transplantations. Due to intolerance or resistance to the current immunomodulatory treatments, the management of FSGS is a therapeutic challenge. Over the last few years, development in extracorporeal therapies has shown potential beneficial outcomes in drug-resistant and recurrent FSGS patients. Thus, this study reviews the current literature on the use of extracorporeal therapies, such as plasma exchange therapy, immunoadsorption, and low-density lipoprotein apheresis, for the treatment of FSGS in the pediatric population.

Original languageEnglish (US)
Pages (from-to)513-523
Number of pages11
JournalBlood Purification
Volume49
Issue number5
DOIs
StatePublished - Sep 1 2020

ASJC Scopus subject areas

  • Hematology
  • Nephrology

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