Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency

Shelley Hancock, Curtis Froehlich, Veronica Armijogarcia, Andrew D Meyer

Research output: Contribution to journalArticle

Abstract

Introduction: Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry. Case Report: A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support. Discussion: The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO. Conclusion: ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.

Original languageEnglish (US)
JournalPerfusion (United Kingdom)
DOIs
StateAccepted/In press - May 1 2018

Fingerprint

Extracorporeal Membrane Oxygenation
Oxygenation
Thorax
Membranes
deformity
organization
Respiratory Insufficiency
contagious disease
Registries
mortality
Organizations
cause
Ribs
Human Influenza
Pneumonia
Spine
Lung
Survival
Mortality
Population

Keywords

  • extracorporeal membrane oxygenation
  • Jeune syndrome
  • pediatrics
  • thoracic insufficiency
  • thoracic surgery

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

Cite this

Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency. / Hancock, Shelley; Froehlich, Curtis; Armijogarcia, Veronica; Meyer, Andrew D.

In: Perfusion (United Kingdom), 01.05.2018.

Research output: Contribution to journalArticle

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