Extracorporeal membrane oxygenation support in individuals with thoracic insufficiency

Shelley Hancock, Curtis Froehlich, Veronica Armijo-Garcia, Andrew D. Meyer

Research output: Contribution to journalArticlepeer-review


Introduction: Respiratory failure is the leading cause of mortality in individuals with congenital spine and rib deformities. We present a case report of a child with Jeune syndrome surviving respiratory failure using extracorporeal membrane oxygenation (ECMO). We also summarize thoracic insufficiency syndrome cases reported in the Extracorporeal Life Support Organization (ELSO) registry. Case Report: A two-year-old male with a chest circumference less than a third percentile for age was admitted with influenza pneumonia developing a peak oxygenation index of 103.5. The child survived to baseline pulmonary function after nine days of venous-arterial ECMO support. Discussion: The ELSO registry contained 27 individuals with a surrogate diagnosis of thoracic insufficiency (0.05%). There was no significant difference in survival to discharge for thoracic insufficiency patients (52%) compared to a previously healthy population supported with ECMO. Conclusion: ECMO is safe and may be effective in supporting individuals with thoracic insufficiency.

Original languageEnglish (US)
Pages (from-to)696-698
Number of pages3
JournalPerfusion (United Kingdom)
Issue number8
StatePublished - Nov 1 2018


  • Jeune syndrome
  • extracorporeal membrane oxygenation
  • pediatrics
  • thoracic insufficiency
  • thoracic surgery

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging
  • Advanced and Specialized Nursing
  • Safety Research


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