Extensive transcription of foreign DNA in a crown gall teratoma

Funmei Yang; Joan C. McPherson; Milton P. Gordon; Eugene W. Nester

doi:10.1016/0006-291X(80)90424-6

Extensive transcription of foreign DNA in a crown gall teratoma

Funmei Yang, Joan C. McPherson, Milton P. Gordon, Eugene W. Nester

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

Original language	English (US)
Pages (from-to)	1273-1277
Number of pages	5
Journal	Biochemical and Biophysical Research Communications
Volume	92
Issue number	4
DOIs	https://doi.org/10.1016/0006-291X(80)90424-6
State	Published - Feb 27 1980
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(80)90424-6

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title = "Extensive transcription of foreign DNA in a crown gall teratoma",

abstract = "We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.",

author = "Funmei Yang and McPherson, {Joan C.} and Gordon, {Milton P.} and Nester, {Eugene W.}",

note = "Funding Information: in the preparation Bst I and BST EII were supported by Public Institute.",

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AU - Yang, Funmei

AU - McPherson, Joan C.

AU - Gordon, Milton P.

AU - Nester, Eugene W.

N1 - Funding Information: in the preparation Bst I and BST EII were supported by Public Institute.

PY - 1980/2/27

Y1 - 1980/2/27

N2 - We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

AB - We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

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U2 - 10.1016/0006-291X(80)90424-6

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JF - Biochemical and Biophysical Research Communications

SN - 0006-291X

IS - 4

ER -

Extensive transcription of foreign DNA in a crown gall teratoma

Abstract

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