Extensive transcription of foreign DNA in a crown gall teratoma

Funmei Yang, Joan C. McPherson, Milton P. Gordon, Eugene W. Nester

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

Original languageEnglish (US)
Pages (from-to)1273-1277
Number of pages5
JournalBiochemical and Biophysical Research Communications
Volume92
Issue number4
DOIs
StatePublished - Feb 27 1980
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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