Expression of Fc and complement receptors on T lymphocytes activated in vitro by phytohaemagglutinin (PHA)

R. S. Smeraldi, M. G. Villa, B. Perussia, G. Fabio, P. Casali, C. Rugarli

Research output: Contribution to journalArticlepeer-review

Abstract

In this work T-enriched lymphocyte populations (obtained from Ig-anti-Ig- Degalan-coated columns) were studied for their surface markers, especially for Fc and complement receptors, before and after a pulse-PHA-stimulation. It has been demonstrated that activated T lymphocytes express on their surface both of these markers in high percentage. The hypothesis is discussed that B and T lymphocytes differ only with regard to the presence of surface immunoglobulins or the ability of forming spontaneous rosettes. On the contrary the other surface markers may probably be expressed when needed functionally by the cells.

Original languageEnglish (US)
Pages (from-to)827-830
Number of pages4
JournalImmunology
Volume32
Issue number6
StatePublished - Dec 1 1977
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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