Expression of cloned β-endorphin gene sequences by Escherichia coli

John Shine, Ivy Fettes, Nancy C.Y. Lan, James L. Roberts, John D. Baxter

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

DNA coding for the opiate peptide β-endorphin has been cloned into bacterial plasmids in such a way as to direct the synthesis of a hybrid β-galactosidase/β-endorphin protein. This hybrid protein can readily be cleaved in vitro to release biologically active β-endorphin.

Original languageEnglish (US)
Pages (from-to)456-461
Number of pages6
JournalNature
Volume285
Issue number5765
DOIs
StatePublished - Dec 1 1980

    Fingerprint

ASJC Scopus subject areas

  • General

Cite this

Shine, J., Fettes, I., Lan, N. C. Y., Roberts, J. L., & Baxter, J. D. (1980). Expression of cloned β-endorphin gene sequences by Escherichia coli. Nature, 285(5765), 456-461. https://doi.org/10.1038/285456a0