Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Heather M. Snyder; Tim Ahles; Stuart Calderwood; Maria C. Carrillo; Honglei Chen; Chung Chou H. Chang; Suzanne Craft; Philip De Jager; Jane A. Driver; Howard Fillit; David Knopman; Michael Lotze; Mary C. Tierney; Suzana Petanceska; Andrew Saykin; Sudha Seshadri; Diana Shineman; Mary Ganguli

doi:10.1016/j.jalz.2016.11.002

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Heather M. Snyder
, Tim Ahles
, Stuart Calderwood
, Maria C. Carrillo
, Honglei Chen
, Chung Chou H. Chang
, Suzanne Craft
, Philip De Jager
, Jane A. Driver
, Howard Fillit
, David Knopman
, Michael Lotze
, Mary C. Tierney
, Suzana Petanceska
, Andrew Saykin
, Sudha Seshadri
, Diana Shineman
, Mary Ganguli

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action.

Original language	English (US)
Pages (from-to)	267-273
Number of pages	7
Journal	Alzheimer's and Dementia
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/j.jalz.2016.11.002
State	Published - Mar 1 2017
Externally published	Yes

Keywords

Alzheimer's disease
Biological mechanisms
Cancer
Epidemiology
Genetics
Oncology
Repurpose therapy

ASJC Scopus subject areas

Epidemiology
Health Policy
Developmental Neuroscience
Clinical Neurology
Geriatrics and Gerontology
Cellular and Molecular Neuroscience
Psychiatry and Mental health

Access to Document

10.1016/j.jalz.2016.11.002

Cite this

Snyder, H. M., Ahles, T., Calderwood, S., Carrillo, M. C., Chen, H., Chang, C. C. H., Craft, S., De Jager, P., Driver, J. A., Fillit, H., Knopman, D., Lotze, M., Tierney, M. C., Petanceska, S., Saykin, A., Seshadri, S., Shineman, D., & Ganguli, M. (2017). Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Alzheimer's and Dementia, 13(3), 267-273. https://doi.org/10.1016/j.jalz.2016.11.002

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. / Snyder, Heather M.; Ahles, Tim; Calderwood, Stuart et al.
In: Alzheimer's and Dementia, Vol. 13, No. 3, 01.03.2017, p. 267-273.

Research output: Contribution to journal › Review article › peer-review

Snyder, HM, Ahles, T, Calderwood, S, Carrillo, MC, Chen, H, Chang, CCH, Craft, S, De Jager, P, Driver, JA, Fillit, H, Knopman, D, Lotze, M, Tierney, MC, Petanceska, S, Saykin, A, Seshadri, S, Shineman, D & Ganguli, M 2017, 'Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation', Alzheimer's and Dementia, vol. 13, no. 3, pp. 267-273. https://doi.org/10.1016/j.jalz.2016.11.002

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abstract = "Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action.",

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doi = "10.1016/j.jalz.2016.11.002",

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AB - Recent population studies suggest an intriguing inverse relationship between several types of cancer and neurodegenerative diseases, including Alzheimer's disease. Understanding the intersection of the underlying biology for these two distinct families of diseases with one another may offer novel approaches to identify new therapeutic approaches and possible opportunities to repurpose existing drug candidates. The Alzheimer's Association and the Alzheimer's Drug Discovery Foundation convened a one-day workshop to delve into this discussion. Workshop participants outlined research focus areas, potential collaborations, and partnerships for future action.

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KW - Biological mechanisms

KW - Cancer

KW - Epidemiology

KW - Genetics

KW - Oncology

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Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: A convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation

Abstract

Keywords

ASJC Scopus subject areas

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