Experimental treatment of Curvularia infection

Katihuska Paredes, Javier Capilla, Deanna A. Sutton, Emilio Mayayo, Annette W. Fothergill, Josep Guarro

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

We have evaluated the efficacy of amphotericin B, posaconazole, and voriconazole in immunosuppressed murine models of disseminated infection by Curvularia spicifera and Curvularia hawaiiensis. The 3 antifungals improved survival of mice in comparison to controls; however, only the 2 azoles were able to reduce significantly the fungal load.

Original languageEnglish (US)
Pages (from-to)428-431
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume79
Issue number4
DOIs
StatePublished - Aug 2014

Keywords

  • Animal model
  • Bipolaris hawaiiensis
  • Bipolaris spicifera
  • Curvularia
  • Fungal infection

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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