Expandable intrahepatic portacaval shunt stents in dogs with chronic portal hypertension

Julio C Palmaz; F. Garcia; R. R. Sibbitt; F. O. Tio; D. T. Kopp; W. Schwesinger; J. L. Lancaster; P. Chang

doi:10.2214/ajr.147.6.1251

Expandable intrahepatic portacaval shunt stents in dogs with chronic portal hypertension

Julio C Palmaz, F. Garcia, R. R. Sibbitt, F. O. Tio, D. T. Kopp, W. Schwesinger, J. L. Lancaster, P. Chang

Department of Surgery

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Abstract

A canine experimental model was used to investigate the feasibility of using balloon-expandable portacaval shunts in humans with chronic portal hypertension. Intrahepatic portacaval shunts were created in nine dogs with stable portal hypertension previously induced by intraportal injections of polyvinyl alcohol (Ivalon). Embolic material was injected periodically through a subcutaneous port that allowed repeated access to the portal system. Shunts were placed 14 weeks after the last embolization. A shunt patency rate of 100% was observed up to 48 weeks. Low portacaval pressure gradient and high shunt flow accounted for the good results.

Original language	English (US)
Pages (from-to)	1251-1254
Number of pages	4
Journal	American Journal of Roentgenology
Volume	147
Issue number	6
DOIs	https://doi.org/10.2214/ajr.147.6.1251
State	Published - 1986

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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title = "Expandable intrahepatic portacaval shunt stents in dogs with chronic portal hypertension",

abstract = "A canine experimental model was used to investigate the feasibility of using balloon-expandable portacaval shunts in humans with chronic portal hypertension. Intrahepatic portacaval shunts were created in nine dogs with stable portal hypertension previously induced by intraportal injections of polyvinyl alcohol (Ivalon). Embolic material was injected periodically through a subcutaneous port that allowed repeated access to the portal system. Shunts were placed 14 weeks after the last embolization. A shunt patency rate of 100% was observed up to 48 weeks. Low portacaval pressure gradient and high shunt flow accounted for the good results.",

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AU - Palmaz, Julio C

AU - Garcia, F.

AU - Sibbitt, R. R.

AU - Tio, F. O.

AU - Kopp, D. T.

AU - Schwesinger, W.

AU - Lancaster, J. L.

AU - Chang, P.

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Expandable intrahepatic portacaval shunt stents in dogs with chronic portal hypertension

Abstract

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