Expandable intrahepatic portacaval shunt stents in dogs with chronic portal hypertension

J. C. Palmaz, F. Garcia, R. R. Sibbitt, F. O. Tio, D. T. Kopp, W. Schwesinger, J. L. Lancaster, P. Chang

Research output: Contribution to journalArticlepeer-review

82 Scopus citations

Abstract

A canine experimental model was used to investigate the feasibility of using balloon-expandable portacaval shunts in humans with chronic portal hypertension. Intrahepatic portacaval shunts were created in nine dogs with stable portal hypertension previously induced by intraportal injections of polyvinyl alcohol (Ivalon). Embolic material was injected periodically through a subcutaneous port that allowed repeated access to the portal system. Shunts were placed 14 weeks after the last embolization. A shunt patency rate of 100% was observed up to 48 weeks. Low portacaval pressure gradient and high shunt flow accounted for the good results.

Original languageEnglish (US)
Pages (from-to)1251-1254
Number of pages4
JournalAmerican Journal of Roentgenology
Volume147
Issue number6
DOIs
StatePublished - 1986

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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