Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects

Chen Wei; Meera Penumetcha; Nalini Santanam; Ya Guang Liu; Mahdi Garelnabi; Sampath Parthasarathy

doi:10.1016/j.bbagen.2005.03.005

Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects

Chen Wei
, Meera Penumetcha
, Nalini Santanam
, Ya Guang Liu
, Mahdi Garelnabi
, Sampath Parthasarathy

Department of Pathology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARγ) ligands.

Original language	English (US)
Pages (from-to)	124-127
Number of pages	4
Journal	Biochimica et Biophysica Acta - General Subjects
Volume	1723
Issue number	1-3
DOIs	https://doi.org/10.1016/j.bbagen.2005.03.005
State	Published - May 25 2005

Keywords

Atherosclerosis
Exercise
PPAR
Scavenger receptors

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology

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10.1016/j.bbagen.2005.03.005

Cite this

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title = "Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects",

abstract = "Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARγ) ligands.",

keywords = "Atherosclerosis, Exercise, PPAR, Scavenger receptors",

author = "Chen Wei and Meera Penumetcha and Nalini Santanam and Liu, \{Ya Guang\} and Mahdi Garelnabi and Sampath Parthasarathy",

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doi = "10.1016/j.bbagen.2005.03.005",

language = "English (US)",

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T2 - Potential mechanism for its anti-atherosclerotic effects

AU - Wei, Chen

AU - Penumetcha, Meera

AU - Santanam, Nalini

AU - Liu, Ya Guang

AU - Garelnabi, Mahdi

AU - Parthasarathy, Sampath

PY - 2005/5/25

Y1 - 2005/5/25

N2 - Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARγ) ligands.

AB - Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARγ) ligands.

KW - Atherosclerosis

KW - Exercise

KW - PPAR

KW - Scavenger receptors

UR - https://www.scopus.com/pages/publications/19744367487

UR - https://www.scopus.com/pages/publications/19744367487#tab=citedBy

U2 - 10.1016/j.bbagen.2005.03.005

DO - 10.1016/j.bbagen.2005.03.005

M3 - Article

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AN - SCOPUS:19744367487

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JO - Biochimica et Biophysica Acta - General Subjects

JF - Biochimica et Biophysica Acta - General Subjects

IS - 1-3

ER -

Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects

Abstract

Keywords

ASJC Scopus subject areas

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