Exercise might favor reverse cholesterol transport and lipoprotein clearance: Potential mechanism for its anti-atherosclerotic effects

Chen Wei, Meera Penumetcha, Nalini Santanam, Ya Guang Liu, Mahdi Garelnabi, Sampath Parthasarathy

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Livers of C57 BL/6 mice exercised for 2 weeks showed a dramatic increase in scavenger receptor B1 (SR-B1), CD36 and low density lipoprotein (LDL) receptor and a decrease in acetyl LDL receptor gene expression. These effects on lipoprotein receptors are reminiscent of the effects mediated by peroxisome proliferator-activated receptor (PPARγ) ligands.

Original languageEnglish (US)
Pages (from-to)124-127
Number of pages4
JournalBiochimica et Biophysica Acta - General Subjects
Volume1723
Issue number1-3
DOIs
StatePublished - May 25 2005

Keywords

  • Atherosclerosis
  • Exercise
  • PPAR
  • Scavenger receptors

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology

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