Excretion of Na+, K+, Cl-, and HCO3 - in the Saliva of the Rhesus Monkey (34843)

James E. Bruckman, John A. Mangos

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The excretion of sodium, potassium, chloride and bicarbonate in the parotid and submaxillary saliva was studied in five young adult monkeys (M. mulatta). After stimulation of the glands with pilocarpine (1.0-1.5 mg) injected intravenously, saliva was collected at progressively decreasing flow rates until the flow of saliva stopped. The glands were dissected and weighed, and flow rates were expressed as μ/min/g wet gland tissue. The concentrations of ions were related to flow rate. Sodium and bicarbonate concentrations were low at low flow rates and increased to a plateau with increasing flow rates. Potassium and chloride concentrations were high at low flow rates and gradually decreased with increasing flow rates. These patterns of excretion of ions were similar to those observed in man, suggesting that the rhesus monkey, an animal phylogenetically closely related to man, is suitable for experimental studies of salivary gland function.

Original languageEnglish (US)
Pages (from-to)606-610
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume134
Issue number3
DOIs
StatePublished - 1970
Externally publishedYes

Fingerprint

Macaca mulatta
Saliva
Sodium Bicarbonate
Potassium Chloride
Flow rate
Ions
Pilocarpine
Salivary Glands
Sodium Chloride
Haplorhini
Young Adult
Animals
Sodium
Tissue

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Excretion of Na+, K+, Cl-, and HCO3 - in the Saliva of the Rhesus Monkey (34843). / Bruckman, James E.; Mangos, John A.

In: Proceedings of the Society for Experimental Biology and Medicine, Vol. 134, No. 3, 1970, p. 606-610.

Research output: Contribution to journalArticle

@article{0d0d970bfdcb4f04a4940d4dbc60db09,
title = "Excretion of Na+, K+, Cl-, and HCO3 - in the Saliva of the Rhesus Monkey (34843)",
abstract = "The excretion of sodium, potassium, chloride and bicarbonate in the parotid and submaxillary saliva was studied in five young adult monkeys (M. mulatta). After stimulation of the glands with pilocarpine (1.0-1.5 mg) injected intravenously, saliva was collected at progressively decreasing flow rates until the flow of saliva stopped. The glands were dissected and weighed, and flow rates were expressed as μ/min/g wet gland tissue. The concentrations of ions were related to flow rate. Sodium and bicarbonate concentrations were low at low flow rates and increased to a plateau with increasing flow rates. Potassium and chloride concentrations were high at low flow rates and gradually decreased with increasing flow rates. These patterns of excretion of ions were similar to those observed in man, suggesting that the rhesus monkey, an animal phylogenetically closely related to man, is suitable for experimental studies of salivary gland function.",
author = "Bruckman, {James E.} and Mangos, {John A.}",
year = "1970",
doi = "10.3181/00379727-134-34843",
language = "English (US)",
volume = "134",
pages = "606--610",
journal = "Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)",
issn = "1535-3702",
publisher = "Society for Experimental Biology and Medicine",
number = "3",

}

TY - JOUR

T1 - Excretion of Na+, K+, Cl-, and HCO3 - in the Saliva of the Rhesus Monkey (34843)

AU - Bruckman, James E.

AU - Mangos, John A.

PY - 1970

Y1 - 1970

N2 - The excretion of sodium, potassium, chloride and bicarbonate in the parotid and submaxillary saliva was studied in five young adult monkeys (M. mulatta). After stimulation of the glands with pilocarpine (1.0-1.5 mg) injected intravenously, saliva was collected at progressively decreasing flow rates until the flow of saliva stopped. The glands were dissected and weighed, and flow rates were expressed as μ/min/g wet gland tissue. The concentrations of ions were related to flow rate. Sodium and bicarbonate concentrations were low at low flow rates and increased to a plateau with increasing flow rates. Potassium and chloride concentrations were high at low flow rates and gradually decreased with increasing flow rates. These patterns of excretion of ions were similar to those observed in man, suggesting that the rhesus monkey, an animal phylogenetically closely related to man, is suitable for experimental studies of salivary gland function.

AB - The excretion of sodium, potassium, chloride and bicarbonate in the parotid and submaxillary saliva was studied in five young adult monkeys (M. mulatta). After stimulation of the glands with pilocarpine (1.0-1.5 mg) injected intravenously, saliva was collected at progressively decreasing flow rates until the flow of saliva stopped. The glands were dissected and weighed, and flow rates were expressed as μ/min/g wet gland tissue. The concentrations of ions were related to flow rate. Sodium and bicarbonate concentrations were low at low flow rates and increased to a plateau with increasing flow rates. Potassium and chloride concentrations were high at low flow rates and gradually decreased with increasing flow rates. These patterns of excretion of ions were similar to those observed in man, suggesting that the rhesus monkey, an animal phylogenetically closely related to man, is suitable for experimental studies of salivary gland function.

UR - http://www.scopus.com/inward/record.url?scp=84970302267&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84970302267&partnerID=8YFLogxK

U2 - 10.3181/00379727-134-34843

DO - 10.3181/00379727-134-34843

M3 - Article

C2 - 4988177

AN - SCOPUS:84970302267

VL - 134

SP - 606

EP - 610

JO - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

JF - Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N. Y.)

SN - 1535-3702

IS - 3

ER -