Evidence supports no relationship between obstructive sleep apnea and premolar extraction: An electronic health records review

Ann Larsen, D. Brad Rindal, John P. Hatch, Sheryl Kane, Stephen E. Asche, Chris Carvalho, John D Rugh

Research output: Contribution to journalArticle

7 Scopus citations


Objective: A controversy exists concerning the relationship, if any, between obstructive sleep apnea (OSA) and the anatomical position of the anterior teeth. Specifically, there has been speculation that extraction orthodontics and retraction of the anterior teeth contributes to OSA by crowding the tongue and decreasing airway space. This retrospective study utilized electronic medical and dental health records to examine the association between missing premolars and OSA. Methods: The sample (n = 5,584) was obtained from the electronic medical and dental health records of HealthPartners in Minnesota. Half of the subjects (n = 2,792) had one missing premolar in each quadrant. The other half had no missing premolars. Cases and controls were paired in a 1:1 match on age range, gender, and body mass index (BMI) range. The outcome was the presence or absence of a diagnosis of OSA confirmed by polysomnography. Results: Of the subjects without missing premolars, 267 (9.56%) had received a diagnosis of OSA. Of the subjects with four missing premolars, 299 (10.71%) had received a diagnosis of OSA. The prevalence of OSA was not significantly different between the groups (OR = 1.14, p = 0.144). Conclusion: The absence of four premolars (one from each quadrant), and therefore a presumed indicator of past "extraction orthodontic treatment," is not supported as a significant factor in the cause of OSA.

Original languageEnglish (US)
Pages (from-to)1443-1448
Number of pages6
JournalJournal of Clinical Sleep Medicine
Issue number12
Publication statusPublished - 2015



  • Airway space
  • Obstructive sleep apnea
  • Orthodontic treatment
  • Polysomnogram
  • Premolar extraction

ASJC Scopus subject areas

  • Clinical Neurology
  • Pulmonary and Respiratory Medicine
  • Neurology

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