Evidence-based recommendations for the prevention and long-term management of thrombosis in antiphospholipid antibody-positive patients: Report of a Task Force at the 13th International Congress on Antiphospholipid Antibodies

G. Ruiz-Irastorza, M. J. Cuadrado, I. Ruiz-Arruza, R. Brey, M. Crowther, R. Derksen, D. Erkan, S. Krilis, S. Machin, V. Pengo, S. Pierangeli, M. Tektonidou, M. Khamashta

Research output: Contribution to journalArticlepeer-review

328 Scopus citations

Abstract

The antiphospholipid syndrome (APS) is defined by the presence of thrombosis and/or pregnancy morbidity in combination with the persistent presence of circulating antiphospholipid antibodies: lupus anticoagulant, anticardiolipin antibodies and/or anti-β2-glycoprotein I antibodies in medium to high titers. The management of thrombosis in patients with APS is a subject of controversy. This set of recommendations is the result of an effort to produce guidelines for therapy within a group of specialist physicians in Cardiology, Neurology, Hematology, Rheumatology and Internal Medicine, with a clinical and research focus on APS.

Original languageEnglish (US)
Pages (from-to)206-218
Number of pages13
JournalLupus
Volume20
Issue number2
DOIs
StatePublished - Feb 1 2011

Keywords

  • anticardiolipin
  • antiphospholipid
  • aspirin
  • hydroxychloroquine
  • lupus anticoagulant
  • prevention
  • stroke
  • thrombosis
  • warfarin

ASJC Scopus subject areas

  • Rheumatology

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