Evaluation of the specificity and sensitivity of a potential rapid influenza screening system

Luis E. Perez, Gerald A. Merrill, Robert A. DeLorenzo, Thomas W. Schoenfeld, Abhay Vats, Michael J. Moser

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Influenza remains a serious worldwide health threat with numerous deaths attributed to influenza-related complications. It is likely that transmission of influenza and both the morbidity and mortality of influenza could be reduced if inexpensive but reliable influenza screening assays were more available to the general public or local medical treatment facilities. This report provides the initial evaluation of a pilot system designed by Lucigen Corp. (Middleton, WI, USA) as a potential rapid near point-of-care screening system for influenza A and influenza B. The evaluation of specificity and sensitivity was conducted on stored nasal swab samples collected from emergency department patients presenting with influenza-like symptoms at a large military academic hospital and on de-identified nasal swabs and isolated RNA from a local epidemiology laboratory. The gold standard for assessment of specificity and sensitivity was the Luminex® Respiratory Viral Panel.

Original languageEnglish (US)
Pages (from-to)77-80
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Issue number1
StatePublished - Jan 2013
Externally publishedYes


  • Influenza A and B
  • Isothermal PCR
  • PyroScript
  • RVP

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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