Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents

C. M. Agrawal; K. F. Haas; D. A. Leopold; H. G. Clark

doi:10.1016/0142-9612(92)90068-Y

Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents

C. M. Agrawal, K. F. Haas, D. A. Leopold, H. G. Clark

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Abstract

Poly(l-lactic acid) (PLLA) monofilaments were evaluated for use as intravascular polymeric stents. The PLLA monofilaments were extruded and drawn to different draw ratios. They were then subjected to different thermal treatments and their mechanical properties characterized. Stents constructed with similar monofilaments were tested under hydrostatic pressure, and the results correlated with the properties of the monofilaments. Stent collapse pressure was a decreasing function of stent diameter and filament draw ratio.

Original language	English (US)
Pages (from-to)	176-182
Number of pages	7
Journal	Biomaterials
Volume	13
Issue number	3
DOIs	https://doi.org/10.1016/0142-9612(92)90068-Y
State	Published - 1992

Keywords

Poly(lactic acid)
mechanical properties
vascular stents

ASJC Scopus subject areas

Bioengineering
Ceramics and Composites
Biophysics
Biomaterials
Mechanics of Materials

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10.1016/0142-9612(92)90068-Y

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title = "Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents",

abstract = "Poly(l-lactic acid) (PLLA) monofilaments were evaluated for use as intravascular polymeric stents. The PLLA monofilaments were extruded and drawn to different draw ratios. They were then subjected to different thermal treatments and their mechanical properties characterized. Stents constructed with similar monofilaments were tested under hydrostatic pressure, and the results correlated with the properties of the monofilaments. Stent collapse pressure was a decreasing function of stent diameter and filament draw ratio.",

keywords = "Poly(lactic acid), mechanical properties, vascular stents",

author = "Agrawal, {C. M.} and Haas, {K. F.} and Leopold, {D. A.} and Clark, {H. G.}",

note = "Funding Information: The authors are grateful for the help and advice provided by Drs R.S. Stack, G.W. Pearsall and J. McElhaney. Thanks also are due to Dr A. Schindler of the Research Triangle Institute, North Carolina, for assistance with gel permeation chromatography, and to Seiko Instruments Inc. for their help with the dynamic mechanical analysis. The support of the National Science Foundation{\textquoteright}s Engineering Research Center for Emerging Cardiovascular Technologies at Duke University also is acknowledged.",

year = "1992",

doi = "10.1016/0142-9612(92)90068-Y",

language = "English (US)",

volume = "13",

pages = "176--182",

journal = "Biomaterials",

issn = "0142-9612",

publisher = "Elsevier BV",

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T1 - Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents

AU - Agrawal, C. M.

AU - Haas, K. F.

AU - Leopold, D. A.

AU - Clark, H. G.

N1 - Funding Information: The authors are grateful for the help and advice provided by Drs R.S. Stack, G.W. Pearsall and J. McElhaney. Thanks also are due to Dr A. Schindler of the Research Triangle Institute, North Carolina, for assistance with gel permeation chromatography, and to Seiko Instruments Inc. for their help with the dynamic mechanical analysis. The support of the National Science Foundation’s Engineering Research Center for Emerging Cardiovascular Technologies at Duke University also is acknowledged.

PY - 1992

Y1 - 1992

N2 - Poly(l-lactic acid) (PLLA) monofilaments were evaluated for use as intravascular polymeric stents. The PLLA monofilaments were extruded and drawn to different draw ratios. They were then subjected to different thermal treatments and their mechanical properties characterized. Stents constructed with similar monofilaments were tested under hydrostatic pressure, and the results correlated with the properties of the monofilaments. Stent collapse pressure was a decreasing function of stent diameter and filament draw ratio.

AB - Poly(l-lactic acid) (PLLA) monofilaments were evaluated for use as intravascular polymeric stents. The PLLA monofilaments were extruded and drawn to different draw ratios. They were then subjected to different thermal treatments and their mechanical properties characterized. Stents constructed with similar monofilaments were tested under hydrostatic pressure, and the results correlated with the properties of the monofilaments. Stent collapse pressure was a decreasing function of stent diameter and filament draw ratio.

KW - Poly(lactic acid)

KW - mechanical properties

KW - vascular stents

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JF - Biomaterials

SN - 0142-9612

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ER -

Evaluation of poly(L-lactic acid) as a material for intravascular polymeric stents

Abstract

Keywords

ASJC Scopus subject areas

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