Evaluation of neurolytic blocks using phenol and cryogenic block in the management of chronic pain

Somayaji Ramamurthy, Nicolas E. Walsh, Lawrence S. Schoenfeld, Joan Hoffman

Research output: Contribution to journalArticle

22 Scopus citations


This study compared the use of phenol and cryogenic blocks for neurolysis in 28 patients. Patients were assigned randomly to receive peripheral nerve blocks with either phenol or cryoanalgesia. Significantly more patients in the phenol group received 20% or greater relief at 2, 12, and 24 wk than patients in the cryogenic group. Only 27% of patients received significant relief, however, indicating that neurolytic blocks were not particularly effective even though local anesthetic blocks produced significant but temporary pain relief.

Original languageEnglish (US)
Pages (from-to)72-75
Number of pages4
JournalJournal of Pain and Symptom Management
Issue number2
StatePublished - Jun 1989



  • Neurolytic nerve blocks
  • chronic pain
  • cryoanalgesia
  • phenol

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine

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