Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

George R. Thompson; Annette W. Fothergill; Nathan P. Wiederhold; Ana C. Vallor; Brian L. Wickes; Thomas F. Patterson

doi:10.1128/AAC.00646-08

Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

George R. Thompson
, Annette W. Fothergill
, Nathan P. Wiederhold
, Ana C. Vallor
, Brian L. Wickes
, Thomas F. Patterson

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

Original language	English (US)
Pages (from-to)	2959-2961
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	52
Issue number	8
DOIs	https://doi.org/10.1128/AAC.00646-08
State	Published - Aug 2008

ASJC Scopus subject areas

Pharmacology (medical)
Infectious Diseases
Pharmacology

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title = "Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans",

abstract = "We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8\% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.",

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AU - Vallor, Ana C.

AU - Wickes, Brian L.

AU - Patterson, Thomas F.

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AB - We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

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AN - SCOPUS:48749109549

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Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

Abstract

ASJC Scopus subject areas

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