Estimating and testing an index of responsiveness and the relationship of the index to power

Michael R. Tuley, Cynthia D. Mulrow, C. Alex McMahan

Research output: Contribution to journalArticlepeer-review

69 Scopus citations

Abstract

Responsiveness has been proposed as a criterion, in addition to reliability and validity, to evaluate instruments that measure quality of life or functional status. The responsiveness index measures the change in a quality of life score due to a treatment relative to the variability of changes in that score within a stable control group. We derive the expected value, variance and distribution of the responsiveness index and give a large sample distribution for comparing the responsiveness of two different instruments. We also give the relationship between the responsiveness index and the power of a test of treatment effect.

Original languageEnglish (US)
Pages (from-to)417-421
Number of pages5
JournalJournal of Clinical Epidemiology
Volume44
Issue number4-5
DOIs
StatePublished - 1991

Keywords

  • Evaluative instrument
  • Power
  • Reliability
  • Responsiveness
  • Sensitivity to change
  • Validity

ASJC Scopus subject areas

  • Epidemiology

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