Estimating and testing an index of responsiveness and the relationship of the index to power

Michael R. Tuley; Cynthia D. Mulrow; C. Alex McMahan

doi:10.1016/0895-4356(91)90080-S

Estimating and testing an index of responsiveness and the relationship of the index to power

Michael R. Tuley, Cynthia D. Mulrow, C. Alex McMahan

Pathology

Research output: Contribution to journal › Article › peer-review

69 Scopus citations

Abstract

Responsiveness has been proposed as a criterion, in addition to reliability and validity, to evaluate instruments that measure quality of life or functional status. The responsiveness index measures the change in a quality of life score due to a treatment relative to the variability of changes in that score within a stable control group. We derive the expected value, variance and distribution of the responsiveness index and give a large sample distribution for comparing the responsiveness of two different instruments. We also give the relationship between the responsiveness index and the power of a test of treatment effect.

Original language	English (US)
Pages (from-to)	417-421
Number of pages	5
Journal	Journal of Clinical Epidemiology
Volume	44
Issue number	4-5
DOIs	https://doi.org/10.1016/0895-4356(91)90080-S
State	Published - 1991

Keywords

Evaluative instrument
Power
Reliability
Responsiveness
Sensitivity to change
Validity

ASJC Scopus subject areas

Epidemiology

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KW - Sensitivity to change

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