Estimates of the half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in vietnam veterans of operation ranch hand

James L. Pirkle, William H. Wolfe, Donald G. Patterson, Larry L. Needham, Joel E. Michalek, Judson C. Miner, Michael R. Peterson, Donald L. Phillips

Research output: Contribution to journalArticle

201 Scopus citations

Abstract

The half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (2, 3, 7, 8-TCDD; commonly known as dioxin) in serum has been measured in 36 Air Force Vietnam veterans of Operation Ranch Hand, which was the operation that aerially sprayed the herbicide Agent Orange in Vietnam. From serum specimens taken in 1982 and 1987, the median half-life of 2, 3, 7, 8-TCDD in these Ranch Hand veterans was found to be 7.1 yr (95% confidence.

Original languageEnglish (US)
Pages (from-to)165-171
Number of pages7
JournalJournal of Toxicology and Environmental Health
Volume27
Issue number2
DOIs
StatePublished - Jun 1 1989

ASJC Scopus subject areas

  • Toxicology
  • Pollution

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    Pirkle, J. L., Wolfe, W. H., Patterson, D. G., Needham, L. L., Michalek, J. E., Miner, J. C., Peterson, M. R., & Phillips, D. L. (1989). Estimates of the half-life of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin in vietnam veterans of operation ranch hand. Journal of Toxicology and Environmental Health, 27(2), 165-171. https://doi.org/10.1080/15287398909531288