Establishing institutional critical values of follicle-stimulating hormone levels to predict in vitro fertilization success

Laura Lee Rihl Joiner, Randal D. Robinson, G. Wright Bates, Anthony M. Propst

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Elevated follicle-stimulating hormone (FSH) levels during the early follicular phase or in response to the clomiphene citrate challenge test indicate diminished ovarian reserve and poor reproductive potential. We performed a retrospective analysis of 413 infertile women, 23 to 40 years of age, who underwent 523 cycles of in vitro fertilization (IVF) to identify the critical FSH values that would predict a poor likelihood of success in our military IVF program. Each woman underwent a clomiphene citrate challenge test within 1 year of each IVF cycle. The overall live birth and implantation rates were 43% and 24%, respectively. The critical values for day 3 and day 10 FSH levels were 14.1 and 16.9 mlU/mL, respectively, with a 0% live birth rate and a 5% implantation rate above these levels. There were no differences in the live birth/implantation rates when stratified for FSH levels below the critical values. Medical centers offering IVF should determine their critical FSH values, to help identify patients unlikely to benefit from IVF and to ensure appropriate allocation of resources and realistic expectations for infertile couples.

Original languageEnglish (US)
Pages (from-to)202-204
Number of pages3
JournalMilitary medicine
Volume172
Issue number2
DOIs
StatePublished - Feb 2007
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Fingerprint Dive into the research topics of 'Establishing institutional critical values of follicle-stimulating hormone levels to predict in vitro fertilization success'. Together they form a unique fingerprint.

Cite this