ESCRTing Necroptosis

Hongyan Guo, William J. Kaiser

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations


Necroptosis is a highly inflammatory form of programmed cell death that results from MLKL-mediated disruption of the cell membrane. In this issue of Cell, Gong et al. challenge the notion that MLKL activation is a point of no return by identifying mechanisms to counterbalance necroptosis, sustain plasma membrane integrity, and prolong cell viability.

Original languageEnglish (US)
Pages (from-to)186-187
Number of pages2
Issue number2
StatePublished - Apr 6 2017

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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