Equilibrium: The intracellular distribution of steroid receptors

Peter J. Sheridan, James M. Buchanan, Vincent C. Anselmo, Pierre M. Martin

Research output: Contribution to journalArticlepeer-review

133 Scopus citations

Abstract

Data are presented which suggest that there are unbound receptors for oestrogen in nuclei of the smooth muscle cells of the myometrium. A new model for the distribution of unbound receptors is proposed in which unbound receptor is in equilibrium, partitioned between nucleus and cytoplasm according to the free water content of these intracellular compartments.

Original languageEnglish (US)
Pages (from-to)579-582
Number of pages4
JournalNature
Volume282
Issue number5739
DOIs
StatePublished - 1979
Externally publishedYes

ASJC Scopus subject areas

  • General

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