Epithelioid osteosarcoma presenting as a rapidly expanding maxillary mass

Joseph Rinaggio, Greg F. Kewitt, H. Stan McGuff

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Background. Osteosarcomas of the jaws account for less than 10% of reported neoplasms of this type. Patients with osteosarcoma in this region tend to be in the late-third to mid-fourth decades of life. The osteoblastic, chondroblastic, and fibroblastic variants constitute the majority of lesions. Methods. A mass was observed in the maxilla of a 50-year-old male who presented for a complete odontectomy. Over the ensuing weeks, the mass substantially increased in size, despite multimodality treatment efforts. Results. Radiographic findings revealed a mixed density mass of the left maxilla. Histologic, immunohistochemical, and electron microscopy examination of the tumor showed a malignant mesenchymal neoplasm consisting of sheets of epithelioid and spindle cells exhibiting focal osteoid formation. Conclusions. We report a rare and aggressive case of epithelioid osteosarcoma arising in the maxillofacial complex.

Original languageEnglish (US)
Pages (from-to)705-709
Number of pages5
JournalHead and Neck
Issue number7
StatePublished - Jul 1 2007
Externally publishedYes


  • Epithelioid
  • Jaws
  • Maxilla
  • Osteosarcoma
  • Sarcoma

ASJC Scopus subject areas

  • Otorhinolaryngology


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