Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells

R. S. Bahn, Kermit V Speeg, M. Ascoli, D. Rabin

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Epidermal growth factor (EGF) stimulates the production of progesterone by JEG-3, a clonal strain of human choriocarcinoma cells. Stimulation occurs in a time and dose-dependent manner. In addition, EGF increases [14C]-acetate incorporation into [14C]-cholesterol in JEG-3 cells, and this may constitute its mechanism of action in enhancing progesterone synthesis.

Original languageEnglish (US)
Pages (from-to)2121-2123
Number of pages3
JournalEndocrinology
Volume107
Issue number6
StatePublished - 1980
Externally publishedYes

Fingerprint

Choriocarcinoma
Epidermal Growth Factor
Progesterone
Acetates
Cholesterol

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Epidermal growth factor stimulates production of progesterone in cultured human choriocarcinoma cells. / Bahn, R. S.; Speeg, Kermit V; Ascoli, M.; Rabin, D.

In: Endocrinology, Vol. 107, No. 6, 1980, p. 2121-2123.

Research output: Contribution to journalArticle

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