Epidemic measles and rubella in air force recruits: Impact of immunization

George E. Crawford, David H. Gremillion

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

The safety of attenuated viral vaccines against measles and rubella and their efficacyin controlling a massive outbreak of these two diseases in air force recruits at Lackland Air Force Base, Texas, were studied. Recorded cases of measles declined from a high of 1,345 in 1976 to a low of 227 in 1979. Similarly, rubella cases declined from a peak before the immunization program of 1,361 in 1977 to a low of 67 in 1979. A controlled study of morbidity related to immunization revealed that there is less immediate local morbidity from immunizations against measles and rubella than with other routine immunizations. Recruits who received the attenuated viral vaccines reported fever, myalgias, and diarrhea only slightly more frequently than did recruits in the concurrent control group. The present data indicate that measles and rubella, increasingly consequential diseases among young adults, can be safelyand effectively controlled with attenuated viral vaccines.

Original languageEnglish (US)
Pages (from-to)403-410
Number of pages8
JournalJournal of Infectious Diseases
Volume144
Issue number5
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases

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