Eosinophilic pneumonia. Physiologic response to steroid therapy and observations on light and electron microscopic findings

R. M. Rogers, J. R. Christiansen, J. J. Coalson, C. D. Patterson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A detailed description is presented of 3 cases of chronic eosinophilic pneumonia, including the clinical features, pulmonary physiologic studies before and after treatment with steroid therapy, and light and electron microscopic studies. All patients showed a dramatic clinical response to steroid therapy, with chest roentgenographic clearing of infiltrates in 2 of 3. Physiologic responses included an increase in vital capacity, arterial oxygen pressure, and single breath CO diffusing capacity, and a decrease in percentage of right-to-left shunt. Electron microscopic examination revealed a marked increase in the cellular content of the alveolar wall interstitium. This disease is of unknown cause but responds clinically and physiologically to steroid therapy, adding another incentive to perform lung biopsies on all patients with diffuse lung disease.

Original languageEnglish (US)
Pages (from-to)665-671
Number of pages7
JournalChest
Volume68
Issue number5
StatePublished - 1975
Externally publishedYes

Fingerprint

Pulmonary Eosinophilia
Steroids
Electrons
Light
Lung
Vital Capacity
Therapeutics
Carbon Monoxide
Lung Diseases
Motivation
Arterial Pressure
Thorax
Oxygen
Biopsy

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Rogers, R. M., Christiansen, J. R., Coalson, J. J., & Patterson, C. D. (1975). Eosinophilic pneumonia. Physiologic response to steroid therapy and observations on light and electron microscopic findings. Chest, 68(5), 665-671.

Eosinophilic pneumonia. Physiologic response to steroid therapy and observations on light and electron microscopic findings. / Rogers, R. M.; Christiansen, J. R.; Coalson, J. J.; Patterson, C. D.

In: Chest, Vol. 68, No. 5, 1975, p. 665-671.

Research output: Contribution to journalArticle

Rogers, RM, Christiansen, JR, Coalson, JJ & Patterson, CD 1975, 'Eosinophilic pneumonia. Physiologic response to steroid therapy and observations on light and electron microscopic findings', Chest, vol. 68, no. 5, pp. 665-671.
Rogers, R. M. ; Christiansen, J. R. ; Coalson, J. J. ; Patterson, C. D. / Eosinophilic pneumonia. Physiologic response to steroid therapy and observations on light and electron microscopic findings. In: Chest. 1975 ; Vol. 68, No. 5. pp. 665-671.
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