Enterococcal superinfection in patients treated with ciprofloxacin

Marcus J. Zervos, Alfred E. Bacon, Jan Evans Patterson, Dennis R. Schaberg, Carol A. Kauffman

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Two patients developed setious enterococcal superinfection following therapy with intravenous ciprofloxacin. The strains causing bacteraemia were susceptible to low concentrations of ciprofloxacin when tested at a standard inoculum. However, at an inoculum of 1 × 107 cfu/ml they were resistant to high concentrations of ciprofloxacin. Our data suggest that ciprofloxacin should not be used to treat patients with serious enterococcal infection and that patients treated with ciprofloxacin should be monitored carefully for the development of enterococcal superinfection.

Original languageEnglish (US)
Pages (from-to)113-115
Number of pages3
JournalJournal of Antimicrobial Chemotherapy
Issue number1
StatePublished - Jan 1988
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Microbiology (medical)
  • Infectious Diseases
  • Pharmacology (medical)


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