Enhancement of surface wettability via the modification of microtextured titanium implant surfaces with polyelectrolytes

Jung Hwa Park, Zvi Schwartz, Rene Olivares-Navarrete, Barbara D. Boyan, Rina Tannenbaum

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Micrometer- and submicrometer-scale surface roughness enhances osteoblast differentiation on titanium (Ti) substrates and increases bone-to-implant contact in vivo. However, the low surface wettability induced by surface roughness can retard initial interactions with the physiological environment. We examined chemical modifications of Ti surfaces [pretreated (PT), Ra ≤ 0.3 μm; sand blasted/acid etched (SLA), Ra ≥ 3.0 μm] in order to modify surface hydrophilicity.We designed coating layers of polyelectrolytes that did not alter the surface microstructure but increased surface ionic character, including chitosan (CHI), poly- (L-glutamic acid) (PGA), and poly(L-lysine) (PLL). Ti disks were cleaned and sterilized. Surface chemical composition, roughness, wettability, and morphology of surfaces before and after polyelectrolyte coating were examined by X-ray photoelectron spectroscopy (XPS), contact mode profilometry, contact angle measurement, and scanning electron microscopy (SEM). High-resolution XPS spectra data validated the formation of polyelectrolyte layers on top of the Ti surface. The surface coverage of the polyelectrolyte adsorbed on Ti surfaces was evaluated with the pertinent SEM images and XPS peak intensity as a function of polyelectrolyte adsorption time on the Ti surface. PLL was coated in a uniform thin layer on the PT surface. CHI and PGA were coated evenly on PT, albeit in an incomplete monolayer. CHI, PGA, and PLL were coated on the SLA surface with complete coverage. The selected polyelectrolytes enhanced surface wettability without modifying surface roughness. These chemically modified surfaces on implant devices can contribute to the enhancement of osteoblast differentiation.

Original languageEnglish (US)
Pages (from-to)5976-5985
Number of pages10
JournalLangmuir
Volume27
Issue number10
DOIs
StatePublished - Jun 1 2011
Externally publishedYes

Fingerprint

wettability
Titanium
Polyelectrolytes
Wetting
titanium
augmentation
glutamic acid
lysine
Chitosan
Surface roughness
Prostaglandins A
Lysine
Glutamic Acid
osteoblasts
surface roughness
X ray photoelectron spectroscopy
Acids
Osteoblasts
photoelectron spectroscopy
coatings

ASJC Scopus subject areas

  • Electrochemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Materials Science(all)
  • Spectroscopy

Cite this

Park, J. H., Schwartz, Z., Olivares-Navarrete, R., Boyan, B. D., & Tannenbaum, R. (2011). Enhancement of surface wettability via the modification of microtextured titanium implant surfaces with polyelectrolytes. Langmuir, 27(10), 5976-5985. https://doi.org/10.1021/la2000415

Enhancement of surface wettability via the modification of microtextured titanium implant surfaces with polyelectrolytes. / Park, Jung Hwa; Schwartz, Zvi; Olivares-Navarrete, Rene; Boyan, Barbara D.; Tannenbaum, Rina.

In: Langmuir, Vol. 27, No. 10, 01.06.2011, p. 5976-5985.

Research output: Contribution to journalArticle

Park, JH, Schwartz, Z, Olivares-Navarrete, R, Boyan, BD & Tannenbaum, R 2011, 'Enhancement of surface wettability via the modification of microtextured titanium implant surfaces with polyelectrolytes', Langmuir, vol. 27, no. 10, pp. 5976-5985. https://doi.org/10.1021/la2000415
Park, Jung Hwa ; Schwartz, Zvi ; Olivares-Navarrete, Rene ; Boyan, Barbara D. ; Tannenbaum, Rina. / Enhancement of surface wettability via the modification of microtextured titanium implant surfaces with polyelectrolytes. In: Langmuir. 2011 ; Vol. 27, No. 10. pp. 5976-5985.
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