Enhanced bone apposition to a chemically modified SLA titanium surface

D. Buser; N. Broggini; M. Wieland; R. K. Schenk; A. J. Denzer; D. L. Cochran; B. Hoffmann; A. Lussi; S. G. Steinemann

doi:10.1177/154405910408300704

Enhanced bone apposition to a chemically modified SLA titanium surface

D. Buser, N. Broggini, M. Wieland, R. K. Schenk, A. J. Denzer, D. L. Cochran, B. Hoffmann, A. Lussi, S. G. Steinemann

Department of Periodontics

Research output: Contribution to journal › Article › peer-review

1053 Scopus citations

Abstract

Increased surface roughness of dental implants has demonstrated greater bone apposition; however, the effect of modifying surface chemistry remains unknown. In the present study, we evaluated bone apposition to a modified sandblasted/acid-etched (modSLA) titanium surface, as compared with a standard SLA surface, during early stages of bone regeneration. Experimental implants were placed in miniature pigs, creating 2 circular bone defects. Test and control implants had the same topography, but differed in surface chemistry. We created the test surface by submerging the implant in an isotonic NaCl solution following acid-etching to avoid contamination with molecules from the atmosphere. Test implants demonstrated a significantly greater mean percentage of bone-implant contact as compared with controls at 2 (49.30 vs. 29.42%; p = 0.017) and 4 wks (81.91 vs. 66.57%; p = 0.011) of healing. At 8 wks, similar results were observed. It is concluded that the modSLA surface promoted enhanced bone apposition during early stages of bone regeneration.

Original language	English (US)
Pages (from-to)	529-533
Number of pages	5
Journal	Journal of dental research
Volume	83
Issue number	7
DOIs	https://doi.org/10.1177/154405910408300704
State	Published - Jul 2004

Keywords

Histomorphometric analysis
Sandblasted and acid-etched surface
Surface chemistry
Surface topography
Titanium surface

ASJC Scopus subject areas

General Dentistry

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10.1177/154405910408300704

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title = "Enhanced bone apposition to a chemically modified SLA titanium surface",

abstract = "Increased surface roughness of dental implants has demonstrated greater bone apposition; however, the effect of modifying surface chemistry remains unknown. In the present study, we evaluated bone apposition to a modified sandblasted/acid-etched (modSLA) titanium surface, as compared with a standard SLA surface, during early stages of bone regeneration. Experimental implants were placed in miniature pigs, creating 2 circular bone defects. Test and control implants had the same topography, but differed in surface chemistry. We created the test surface by submerging the implant in an isotonic NaCl solution following acid-etching to avoid contamination with molecules from the atmosphere. Test implants demonstrated a significantly greater mean percentage of bone-implant contact as compared with controls at 2 (49.30 vs. 29.42%; p = 0.017) and 4 wks (81.91 vs. 66.57%; p = 0.011) of healing. At 8 wks, similar results were observed. It is concluded that the modSLA surface promoted enhanced bone apposition during early stages of bone regeneration.",

keywords = "Histomorphometric analysis, Sandblasted and acid-etched surface, Surface chemistry, Surface topography, Titanium surface",

author = "D. Buser and N. Broggini and M. Wieland and Schenk, {R. K.} and Denzer, {A. J.} and Cochran, {D. L.} and B. Hoffmann and A. Lussi and Steinemann, {S. G.}",

note = "Funding Information: The study was funded by the ITI Foundation for the Promotion of Implantology, Basel, Switzerland (Grant No. 175/1999). The excellent work by Claudia Moser and the staff at the Surgical Research Unit ESI and Clinic for Large Animals, University of Berne, in arranging all surgical procedures is highly appreciated. Experimental implants were provided by Institut Straumann AG, Waldenburg, Switzerland.",

year = "2004",

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doi = "10.1177/154405910408300704",

language = "English (US)",

volume = "83",

pages = "529--533",

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T1 - Enhanced bone apposition to a chemically modified SLA titanium surface

AU - Buser, D.

AU - Broggini, N.

AU - Wieland, M.

AU - Schenk, R. K.

AU - Denzer, A. J.

AU - Cochran, D. L.

AU - Hoffmann, B.

AU - Lussi, A.

AU - Steinemann, S. G.

N1 - Funding Information: The study was funded by the ITI Foundation for the Promotion of Implantology, Basel, Switzerland (Grant No. 175/1999). The excellent work by Claudia Moser and the staff at the Surgical Research Unit ESI and Clinic for Large Animals, University of Berne, in arranging all surgical procedures is highly appreciated. Experimental implants were provided by Institut Straumann AG, Waldenburg, Switzerland.

PY - 2004/7

Y1 - 2004/7

N2 - Increased surface roughness of dental implants has demonstrated greater bone apposition; however, the effect of modifying surface chemistry remains unknown. In the present study, we evaluated bone apposition to a modified sandblasted/acid-etched (modSLA) titanium surface, as compared with a standard SLA surface, during early stages of bone regeneration. Experimental implants were placed in miniature pigs, creating 2 circular bone defects. Test and control implants had the same topography, but differed in surface chemistry. We created the test surface by submerging the implant in an isotonic NaCl solution following acid-etching to avoid contamination with molecules from the atmosphere. Test implants demonstrated a significantly greater mean percentage of bone-implant contact as compared with controls at 2 (49.30 vs. 29.42%; p = 0.017) and 4 wks (81.91 vs. 66.57%; p = 0.011) of healing. At 8 wks, similar results were observed. It is concluded that the modSLA surface promoted enhanced bone apposition during early stages of bone regeneration.

AB - Increased surface roughness of dental implants has demonstrated greater bone apposition; however, the effect of modifying surface chemistry remains unknown. In the present study, we evaluated bone apposition to a modified sandblasted/acid-etched (modSLA) titanium surface, as compared with a standard SLA surface, during early stages of bone regeneration. Experimental implants were placed in miniature pigs, creating 2 circular bone defects. Test and control implants had the same topography, but differed in surface chemistry. We created the test surface by submerging the implant in an isotonic NaCl solution following acid-etching to avoid contamination with molecules from the atmosphere. Test implants demonstrated a significantly greater mean percentage of bone-implant contact as compared with controls at 2 (49.30 vs. 29.42%; p = 0.017) and 4 wks (81.91 vs. 66.57%; p = 0.011) of healing. At 8 wks, similar results were observed. It is concluded that the modSLA surface promoted enhanced bone apposition during early stages of bone regeneration.

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Enhanced bone apposition to a chemically modified SLA titanium surface

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