Endoscopic ultrasound localization of a pancreatic insulinoma: Case report and review of the localization techniques

Randall S. Hall, James F. Hanley, William Georgitis, Peter R. McNally

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

A 23-year-old male was referred to our hospital for evaluation of new- onset seizures. Signs and symptoms of neuroglycopenia, including weakness, dizziness, and confusion, appeared during fasting and resolved promptly with intravenous dextrose administration. Insulin, proinsulin, and C-peptide levels were consistent with a diagnosis of insulinoma. Screening tests for multiple endocrine neoplasia type I and surreptitious sulfonylurea uses were negative. Preoperative localization of the insulinoma by transabdominal ultrasonography, computed tomography, and indium-111 octreoscanning were unsuccessful. Endoscopic ultrasonography (EUS) identified a 6- to 7-mm tumor at the juncture of the head and body of the pancreas. Surgical exploration confirmed the preoperative localization, and an 8-mm tumor was simply enucleated. The patient has been free of symptoms for 18 months since surgery. This report describes the utility of EUS to localize a solitary pancreatic insulinoma and provides a comparison of EUS and other preoperative localization techniques.

Original languageEnglish (US)
Pages (from-to)853-856
Number of pages4
JournalMilitary medicine
Volume163
Issue number12
StatePublished - Dec 1 1998

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

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    Hall, R. S., Hanley, J. F., Georgitis, W., & McNally, P. R. (1998). Endoscopic ultrasound localization of a pancreatic insulinoma: Case report and review of the localization techniques. Military medicine, 163(12), 853-856.