Endoscopic management of Cerebrospinal fluid leaks

J. Drew Sanderson, Stilianos E. Kountakis, K. Christopher McMains

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Cerebrospinal fluid (CSF) rhinorrhea is an uncommon but important medical condition. It can result from trauma, intracranial hypertension, or be idiopathic in origin. If left untreated, significant sequelae can result including infectious meningitis. Beta-2 transferrin is a sensitive and specific protein marker for CSF. Various radiographic modalities have been used to localize defects, including computed tomography (CT), magnetic resonance imaging, and CT cisternography. In recent years, surgical management of this condition has evolved significantly, primarily being performed endoscopically. Reconstruction can be performed with fat, free mucosal, or fascial grafts, or with vascularized flaps. The endoscopic surgeon should have a thorough understanding of the pathophysiology and diagnosis of CSF rhinorrhea as well as several surgical options in his or her armamentarium available to treat the patient suffering from CSF rhinorrhea.

Original languageEnglish (US)
Pages (from-to)29-37
Number of pages9
JournalFacial Plastic Surgery
Issue number1
StatePublished - Feb 2009


  • Anterior skull base surgery
  • Cerebrospinal fluid (CSF) rhinorrhea
  • Cribriform plate
  • Defect repair
  • Nasal endoscopy

ASJC Scopus subject areas

  • Surgery


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