Endometriosis involving the ileocaecal junction with regional lymph node involvement in the baboon - Striking pathological finding identical between the human and the baboon: A case report

B. F. Barrier, E. J. Dick, S. D. Butler, G. B. Hubbard

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The baboon is an established model for endometriosis research. This report describes the occurrence of spontaneous endometriosis involving the ileocaecal junction and associated regional lymph nodes in the baboon. All endometriotic foci lacked the nuclear atypia, abnormal mitotic activity and altered nuclear-to-cytoplasmic ratio typical of malignancy. These findings are identical to reports in the human in which ileocaecal and colonic endometriosis is associated with endometriosis in pericolonic and mesenteric lymph nodes. The similarity between baboon and human colonic endometriosis in both location and pathology is striking and lends further evidence supporting the validity of the baboon as a model for human endometriosis.

Original languageEnglish (US)
Pages (from-to)272-274
Number of pages3
JournalHuman Reproduction
Volume22
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

Keywords

  • Baboon
  • Bowel
  • Colon
  • Endometriosis
  • Lymph node

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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