Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America

Rebeca Rico-Hesse, Scott C. Weaver, Julieta De Siger, Gladys Medina, Rosa Alba Salas

    Research output: Contribution to journalArticlepeer-review

    74 Scopus citations

    Abstract

    One of the most important questions in arbovirology concerns the origin of epidemic Venezuelan equine encephalitis (VEE) viruses; these viruses caused periodic, extensive epidemics/epizootics in the Americas from 1938-1973 (reaching the United States in 1971) but had recently been presumed extinct. We have documented the 1992 emergence of a new epidemic/epizootic VEE virus in Venezuela. Phylogenetic analysis of strains isolated during two outbreaks indicated that the new epidemic/epizootic virus(es) evolved recently from an enzootic VEE virus in northern South America. These results suggest continued emergence of epizootic VEE viruses; surveillance of enzootic viruses and routine vaccination of equines should therefore be resumed.

    Original languageEnglish (US)
    Pages (from-to)5278-5281
    Number of pages4
    JournalProceedings of the National Academy of Sciences of the United States of America
    Volume92
    Issue number12
    DOIs
    StatePublished - Jun 6 1995

    Keywords

    • emerging virus
    • epidemiology
    • molecular evolution

    ASJC Scopus subject areas

    • General

    Fingerprint Dive into the research topics of 'Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America'. Together they form a unique fingerprint.

    Cite this