Electrophoretic variation of supernatant malate dehydrogenase in marsupials

Roger S. Holmes, Guat Kin Chew, Desmond W. Cooper, John L. VandeBerg, William E. Poole

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations


    Starch gel electrophoresis of supernatant malate dehydrogenase (MDH A2) was performed on erythrocyte samples from 505 individual animals representative of 33 marsupial species. Most species exhibited electrophoretically identical forms of MDH A2 activity with the exception of the grey kangaroos, Trichosurus possums, and bandicoots, thus confirming the phylogenetic relatedness of animals within each group and the conservative nature of this enzyme. Polymorphisms were observed in two of the six species analyzed whose mobilities were non-standard. Allelic isozyme patterns and those from interspecies F1 hybrids between grey kangaroos and other macropods were consistent with a dimeric subunit structure and an autosomal locus (MDH-A) encoding the enzyme.

    Original languageEnglish (US)
    Pages (from-to)25-32
    Number of pages8
    JournalBiochemical Genetics
    Issue number1
    StatePublished - Jan 1974


    • isozymes
    • malate dehydrogenase
    • marsupials

    ASJC Scopus subject areas

    • Ecology, Evolution, Behavior and Systematics
    • Biochemistry
    • Molecular Biology
    • Genetics


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