Electrical stimulation of rewarding hypothalamic sites in the 13-lined ground squirrel, Citellus tridecemlineatus, during hibernation: Sensitivity and thermogenic effects

William P Clarke, William C. Hartner

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

1. 1. Ground squirrels were chronically prepared for the determination of hypothalamic stimulus thresholds during hibernation at brain temperatures (Tbr) of 9-15°C by observations of heart rate (HR), neck muscle activity (EMG) and Tbr changes. 2. 2. Preliminary tests on euthermic squirrels showed that the hypothalamic sites were rewarding since animals self-stimulated the sites at a rate proportional to the stimulus intensity. 3. 3. During bouts of hibernation, the threshold for increased HR varied from 2- to 5-fold but did not vary significantly with Tbr or the percentage of the hibernation bout elapsed. 4. 4. Stimulation of the hypothalamus resulted in rises of Tbr during hibernation only if the stimulus produced cardioacceleration.

Original languageEnglish (US)
Pages (from-to)479-486
Number of pages8
JournalComparative Biochemistry and Physiology, Part A
Volume69
Issue number3
StatePublished - 1981
Externally publishedYes

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Hibernation
Sciuridae
Electric Stimulation
Muscle
Brain
Animals
Heart Rate
Neck Muscles
Hypothalamus
Temperature

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Biochemistry

Cite this

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abstract = "1. 1. Ground squirrels were chronically prepared for the determination of hypothalamic stimulus thresholds during hibernation at brain temperatures (Tbr) of 9-15°C by observations of heart rate (HR), neck muscle activity (EMG) and Tbr changes. 2. 2. Preliminary tests on euthermic squirrels showed that the hypothalamic sites were rewarding since animals self-stimulated the sites at a rate proportional to the stimulus intensity. 3. 3. During bouts of hibernation, the threshold for increased HR varied from 2- to 5-fold but did not vary significantly with Tbr or the percentage of the hibernation bout elapsed. 4. 4. Stimulation of the hypothalamus resulted in rises of Tbr during hibernation only if the stimulus produced cardioacceleration.",
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AU - Hartner, William C.

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AB - 1. 1. Ground squirrels were chronically prepared for the determination of hypothalamic stimulus thresholds during hibernation at brain temperatures (Tbr) of 9-15°C by observations of heart rate (HR), neck muscle activity (EMG) and Tbr changes. 2. 2. Preliminary tests on euthermic squirrels showed that the hypothalamic sites were rewarding since animals self-stimulated the sites at a rate proportional to the stimulus intensity. 3. 3. During bouts of hibernation, the threshold for increased HR varied from 2- to 5-fold but did not vary significantly with Tbr or the percentage of the hibernation bout elapsed. 4. 4. Stimulation of the hypothalamus resulted in rises of Tbr during hibernation only if the stimulus produced cardioacceleration.

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