Efficacy of SCH56592 in a rabbit model of invasive aspergillosis

William R. Kirkpatrick, Robert K. McAtee, Annette M Bodi, David Loebenberg, Michael G. Rinaldi, Thomas F. Patterson

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


SCH56592 (SCH) was evaluated in an immunosuppressed rabbit model of invasive aspergillosis. SCH was more effective than similar doses of itraconazole and as effective as amphotericin B in the clearance of Aspergillus spp. from tissues. Compared with controls, SCH regimens reduced mortality, improved survival, and significantly reduced tissue colony counts.

Original languageEnglish (US)
Pages (from-to)780-782
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number3
StatePublished - Mar 2000

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Pharmacology


Dive into the research topics of 'Efficacy of SCH56592 in a rabbit model of invasive aspergillosis'. Together they form a unique fingerprint.

Cite this