Efficacy of caspofungin against Aspergillus terreus

Francesco Barchiesi, Elisabetta Spreghini, Alfredo Santinelli, Annette W. Fothergill, Stefania Fallani, Esther Manso, Eleonora Pisa, Daniele Giannini, Andrea Novelli, Maria I. Cassetta, Teresita Mazzei, Michael G. Rinaldi, Giorgio Scalise

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We investigated the in vitro and in vivo activities of caspofungin against Aspergillus terreus. The drug increased survival and reduced tissue fungal burden in neutropenic mice. Therefore, our data support the role of caspofungin in treating systemic infections due to this emerging pathogen.

Original languageEnglish (US)
Pages (from-to)5133-5135
Number of pages3
JournalAntimicrobial agents and chemotherapy
Volume49
Issue number12
DOIs
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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