Efficacy and tolerability of metallic stent in patients with malignant prostatic obstruction secondary to prostatic cancer

Se Young Choi, Bumjin Lim, Byung Hoon Chi, Jung Hoon Kim, Wonchul Lee, Yoon Soo Kyung, Dalsan You, Ho Young Song, Choung Soo Kim

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the efficacy and tolerability of a self-expandable covered metallic stent in patients with malignant prostatic obstruction secondary to prostate cancer (PC). Methods: We reviewed 22 cases of insertion of self-expandable covered metallic stents with barbs. Data were collected about PC status. Uroflowmetry variables, residual urine volume, International Prostate Symptom Score (IPSS), quality of life (QOL), and duration from stent insertion to removal were surveyed. These clinical parameters were compared before and after stent insertion. Results: The patients with PC showed a mean age of 75.5 ± 6.5 years and mean 5.1 ± 1.9 Charlson comorbidity index. The average flow rate (2.4 ± 1.9 vs 5.9 ± 2.4 mL/s, P =.005), peak flow rate (6.9 ± 6.2 vs 14.1 ± 5.5 mL/s, P =.003), flow time (54.6 ± 29.1 vs 23.6 ± 13.7 s, P =.002), residual urine volume (178.7 ± 195.5 vs 7.0 ± 7.1 mL, P =.004), IPSS (26.2 ± 8.1 vs 8.0 ± 6.5 points, P =.001), and QOL (4.7 ± 1.3 vs 2.4 ± 2.1 points, P =.030) improved between before and after stent insertion, respectively. Pain was the most common complication, but 60% of the patients were managed without any intervention. There were hematuria, urinary retention, urinary frequency, obstruction, and urinary incontinence. However, there was no urinary tract infection due to the stent. The median time to stent removal was 5.7 months. Conclusions: The stent was maintained for about 6 months with improved objective and subjective outcomes. The patients with PC, who had a poor comorbidity index and advanced PC status showed a tolerable maintenance period. Self-expandable covered metallic stents can be used for PC patients with a short life expectancy and unsuitability for general anesthesia.

Original languageEnglish (US)
Pages (from-to)329-334
Number of pages6
JournalLUTS: Lower Urinary Tract Symptoms
Volume13
Issue number3
DOIs
StatePublished - Jul 2021
Externally publishedYes

Keywords

  • barb
  • prostate cancer
  • self-expandable covered metallic stents
  • transurethral resection of the prostate
  • urethral obstruction

ASJC Scopus subject areas

  • Neurology
  • Urology

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