Effects of various feeding and exercise regimens on rat growth and survival

J. D. Yager, M. J. Lichtenstein, R. J. Bonney, H. A. Hopkins, P. R. Walker, C. G. Dorn, V. R. Potter

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


This study was undertaken to obtain additional information on the effects of various feeding and exercise regimens on rat growth and survival. In three experiments, groups of rats, maintained on cycles of 12 hr of light and 12 hr of dark, were trained to various combinations of feeding and voluntary exercise regimens. Rat weights and the amounts of exercise were monitored throughout the experimental periods. At the end of two of the experiments, rats were killed at different times of day, and the weights of several organs were taken. In addition, the activities of several liver enzymes such as tyrosine aminotransferase and ornithine decarboxylase were determined. Data concerning the effects of various combinations of dietary regimens and voluntary exercise indicated that a critical age and period of pretraining on a restricted feeding schedule must be reached to insure that rats will survive repetitive 40 hr fasts after 8 hr feeding periods along with vigorous voluntary exercise. The liver enzyme data indicated that, in surviving rats, the activities of several liver enzymes underwent changes in response to feeding. Some differences between the metabolic states of exercised and nonexercised rats may exist.

Original languageEnglish (US)
Pages (from-to)273-286
Number of pages14
JournalUnknown Journal
Issue number3
StatePublished - 1974
Externally publishedYes

ASJC Scopus subject areas

  • Nutrition and Dietetics
  • Medicine (miscellaneous)


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