Effects of six months of Yoga on inflammatory serum markers prognostic of recurrence risk in breast cancer survivors

Dorothy Longparma, Daniel C Hughes, Sagar Ghosh, Rong Li, Rose A. Treviño-Whitaker, Susan M. Ogden, Amelie G Ramirez

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Yoga-based exercise has proven to be beneficial for practitioners, including cancer survivors. This study reports on the effect on inflammatory biological markers for 20 breast cancer survivors who participated in a six-month yoga-based (YE) exercise program. Results are compared to a comprehensive exercise (CE) program group and a comparison (C) exercise group who chose their own exercises. “Pre” and “post” assessments included measures of anthropometrics, cardiorespiratory capacity, and inflammatory markers interleukin 6 (IL-6), interleukin 8 (IL-8), tumor necrosis factor alpha (TNFα) and C-reactive protein (CRP). Descriptive statistics, effect size (d), and dependent sample ‘t’ tests for all outcome measures were calculated for the YE group. Significant improvements were seen in decreased % body fat, (−3.00%, d = −0.44, p = <.001) but not in cardiorespiratory capacity or in inflammatory serum markers. To compare YE outcomes with the other two groups, a one-way analysis of co-variance (ANCOVA) was used, controlling for age, BMI, cardiorespiratory capacity and serum marker baseline values. We found no differences between groups. Moreover, we did not see significant changes in any inflammatory marker for any group. Our results support the effectiveness of yoga-based exercise modified for breast cancer survivors for improving body composition. Larger studies are needed to determine if there are significant changes in inflammatory serum markers as a result of specific exercise modalities.

Original languageEnglish (US)
Article number143
JournalSpringerPlus
Volume4
Issue number1
DOIs
StatePublished - Dec 28 2015

Fingerprint

Yoga
Biomarkers
Breast Neoplasms
Recurrence
Lymphotoxin-beta
Body Composition
Interleukin-8
C-Reactive Protein
Adipose Tissue
Interleukin-6
Analysis of Variance
Tumor Necrosis Factor-alpha
Outcome Assessment (Health Care)
Neoplasms

Keywords

  • Biomarker
  • Breast cancer survivors
  • Exercise
  • Inflammation
  • Yoga

ASJC Scopus subject areas

  • General

Cite this

Effects of six months of Yoga on inflammatory serum markers prognostic of recurrence risk in breast cancer survivors. / Longparma, Dorothy; Hughes, Daniel C; Ghosh, Sagar; Li, Rong; Treviño-Whitaker, Rose A.; Ogden, Susan M.; Ramirez, Amelie G.

In: SpringerPlus, Vol. 4, No. 1, 143, 28.12.2015.

Research output: Contribution to journalArticle

Longparma, Dorothy ; Hughes, Daniel C ; Ghosh, Sagar ; Li, Rong ; Treviño-Whitaker, Rose A. ; Ogden, Susan M. ; Ramirez, Amelie G. / Effects of six months of Yoga on inflammatory serum markers prognostic of recurrence risk in breast cancer survivors. In: SpringerPlus. 2015 ; Vol. 4, No. 1.
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