Effects of sensory deafferentation on glucose metabolism of muscles during locomotion

E. Eidelberg, Alexander L Miller

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with exercise, but not at rest. Extensor muscles were more affected than flexors by deafferentation. This agrees with the proposal that "reflex" inputs adjust the level of recruitment of motor units by central pattern generators.

Original languageEnglish (US)
Pages (from-to)316-318
Number of pages3
JournalBrain Research
Volume327
Issue number1-2
DOIs
StatePublished - Feb 18 1985

Fingerprint

Locomotion
Glucose
Muscles
Neurophysiological Recruitment
Central Pattern Generators
Walking
Reflex
Extremities

Keywords

  • cats
  • deafferentation
  • dorsal rhizotomy
  • muscle glucose metabolism

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Cite this

Effects of sensory deafferentation on glucose metabolism of muscles during locomotion. / Eidelberg, E.; Miller, Alexander L.

In: Brain Research, Vol. 327, No. 1-2, 18.02.1985, p. 316-318.

Research output: Contribution to journalArticle

Eidelberg, E. ; Miller, Alexander L. / Effects of sensory deafferentation on glucose metabolism of muscles during locomotion. In: Brain Research. 1985 ; Vol. 327, No. 1-2. pp. 316-318.
@article{b6f29e320d48452c89bee05373b91f7f,
title = "Effects of sensory deafferentation on glucose metabolism of muscles during locomotion",
abstract = "We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with exercise, but not at rest. Extensor muscles were more affected than flexors by deafferentation. This agrees with the proposal that {"}reflex{"} inputs adjust the level of recruitment of motor units by central pattern generators.",
keywords = "cats, deafferentation, dorsal rhizotomy, muscle glucose metabolism",
author = "E. Eidelberg and Miller, {Alexander L}",
year = "1985",
month = "2",
day = "18",
doi = "10.1016/0006-8993(85)91526-4",
language = "English (US)",
volume = "327",
pages = "316--318",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "1-2",

}

TY - JOUR

T1 - Effects of sensory deafferentation on glucose metabolism of muscles during locomotion

AU - Eidelberg, E.

AU - Miller, Alexander L

PY - 1985/2/18

Y1 - 1985/2/18

N2 - We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with exercise, but not at rest. Extensor muscles were more affected than flexors by deafferentation. This agrees with the proposal that "reflex" inputs adjust the level of recruitment of motor units by central pattern generators.

AB - We measured the uptake of a radiolabeled analogue of glucose ([3H]FDG) into muscles during treadmill walking so as to determine whether sensory deafferentation of a limb affects the muscles' metabolic response to the exercise. The muscles on the deafferented side took up less tracer than those in the intact side with exercise, but not at rest. Extensor muscles were more affected than flexors by deafferentation. This agrees with the proposal that "reflex" inputs adjust the level of recruitment of motor units by central pattern generators.

KW - cats

KW - deafferentation

KW - dorsal rhizotomy

KW - muscle glucose metabolism

UR - http://www.scopus.com/inward/record.url?scp=0021972215&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021972215&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(85)91526-4

DO - 10.1016/0006-8993(85)91526-4

M3 - Article

C2 - 3986510

AN - SCOPUS:0021972215

VL - 327

SP - 316

EP - 318

JO - Brain Research

JF - Brain Research

SN - 0006-8993

IS - 1-2

ER -