Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model

Don Johnson; James Dial; Jake Ard; Timothy Yourk; Ellen Burke; Craig Paine; Brian Gegel; James Burgert

Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model

Don Johnson, James Dial, Jake Ard, Timothy Yourk, Ellen Burke, Craig Paine, Brian Gegel, James Burgert

Research output: Contribution to journal › Article › peer-review

Abstract

INTRODUCTION: The military recommends that a 500 mL bolus of Hextend® be administered via an intravenous (IV) 18-gauge needle or via an intraosseous (IO) needle for patients in hypovolemic shock.

PURPOSES: The purposes of this study were to compare the time of administration of Hextend and the hemodynamics of IV and IO routes in a Class II hemorrhage swine model.

METHODS: This was an experimental study using 27 swine. After 30% of their blood volume was exsanguinated, 500 mL of Hextend was administered IV or IO, but not to the control group. Hemodynamic data were collected every 2 minutes until administration was complete.

RESULTS: Time for administration was not significant (p=.78). No significant differences existed between the IO and IV groups relative to hemodynamics (p>.05), but both were significantly different than the control group (p<.05).

CONCLUSIONS: The IO route is an effective method of administering Hextend.

Original language	English (US)
Pages (from-to)	79-85
Number of pages	7
Journal	Journal of special operations medicine : a peer reviewed journal for SOF medical professionals
Volume	14
Issue number	1
State	Published - Mar 1 2014
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model. / Johnson, Don; Dial, James; Ard, Jake; Yourk, Timothy; Burke, Ellen; Paine, Craig; Gegel, Brian; Burgert, James.

In: Journal of special operations medicine : a peer reviewed journal for SOF medical professionals, Vol. 14, No. 1, 01.03.2014, p. 79-85.

Research output: Contribution to journal › Article › peer-review

Johnson, Don ; Dial, James ; Ard, Jake ; Yourk, Timothy ; Burke, Ellen ; Paine, Craig ; Gegel, Brian ; Burgert, James. / Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model. In: Journal of special operations medicine : a peer reviewed journal for SOF medical professionals. 2014 ; Vol. 14, No. 1. pp. 79-85.

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title = "Effects of intraosseous and intravenous administration of Hextend{\textregistered} on time of administration and hemodynamics in a Swine model",

abstract = "INTRODUCTION: The military recommends that a 500 mL bolus of Hextend{\textregistered} be administered via an intravenous (IV) 18-gauge needle or via an intraosseous (IO) needle for patients in hypovolemic shock.PURPOSES: The purposes of this study were to compare the time of administration of Hextend and the hemodynamics of IV and IO routes in a Class II hemorrhage swine model.METHODS: This was an experimental study using 27 swine. After 30% of their blood volume was exsanguinated, 500 mL of Hextend was administered IV or IO, but not to the control group. Hemodynamic data were collected every 2 minutes until administration was complete.RESULTS: Time for administration was not significant (p=.78). No significant differences existed between the IO and IV groups relative to hemodynamics (p>.05), but both were significantly different than the control group (p<.05).CONCLUSIONS: The IO route is an effective method of administering Hextend.",

author = "Don Johnson and James Dial and Jake Ard and Timothy Yourk and Ellen Burke and Craig Paine and Brian Gegel and James Burgert",

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T1 - Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model

AU - Johnson, Don

AU - Dial, James

AU - Ard, Jake

AU - Yourk, Timothy

AU - Burke, Ellen

AU - Paine, Craig

AU - Gegel, Brian

AU - Burgert, James

PY - 2014/3/1

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N2 - INTRODUCTION: The military recommends that a 500 mL bolus of Hextend® be administered via an intravenous (IV) 18-gauge needle or via an intraosseous (IO) needle for patients in hypovolemic shock.PURPOSES: The purposes of this study were to compare the time of administration of Hextend and the hemodynamics of IV and IO routes in a Class II hemorrhage swine model.METHODS: This was an experimental study using 27 swine. After 30% of their blood volume was exsanguinated, 500 mL of Hextend was administered IV or IO, but not to the control group. Hemodynamic data were collected every 2 minutes until administration was complete.RESULTS: Time for administration was not significant (p=.78). No significant differences existed between the IO and IV groups relative to hemodynamics (p>.05), but both were significantly different than the control group (p<.05).CONCLUSIONS: The IO route is an effective method of administering Hextend.

AB - INTRODUCTION: The military recommends that a 500 mL bolus of Hextend® be administered via an intravenous (IV) 18-gauge needle or via an intraosseous (IO) needle for patients in hypovolemic shock.PURPOSES: The purposes of this study were to compare the time of administration of Hextend and the hemodynamics of IV and IO routes in a Class II hemorrhage swine model.METHODS: This was an experimental study using 27 swine. After 30% of their blood volume was exsanguinated, 500 mL of Hextend was administered IV or IO, but not to the control group. Hemodynamic data were collected every 2 minutes until administration was complete.RESULTS: Time for administration was not significant (p=.78). No significant differences existed between the IO and IV groups relative to hemodynamics (p>.05), but both were significantly different than the control group (p<.05).CONCLUSIONS: The IO route is an effective method of administering Hextend.

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Effects of intraosseous and intravenous administration of Hextend® on time of administration and hemodynamics in a Swine model

Abstract

ASJC Scopus subject areas

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